Archive for Health and Wellness

Prize4Life Illustrates Collaborative Innovation at Its Best in the Quest to Cure ALS

In Conquering Innovation Fatigue, we emphasize that many innovators are motivated by the desire to make a difference in the world rather than merely obtain personal profit. We also discuss the concept of innovation competitions as a great way to fuel innovation success and access new talent. We also emphasize the importance of collaboration across disciplines and organizational boundaries as the future of innovation success. All these concepts are nicely illustrated by an organization seeking to cure ALS, Lou Gherig’s disease. Prize4Life, Inc. (Prize4Life.org) makes an interesting case study of what can be achieved in the realm of altruistic innovation using collaborative models and innovation competitions.

Meghan Kallman, Marketing & Communications Manager of Prize4Life, Inc. in Cambridge, Massachusetts, kindly shared some information with me about their inspiring innovation efforts. Here is the information she provided:

I would like to share with you the case of Avichai Kremer, co-founder and CEO of Prize4Life, Inc. Then a student at Harvard Business School, Kremer discovered in 2004 that he had ALS (amyotrophic lateral sclerosis, or Lou Gehrig’s Disease).

A computer-science engineer and ex-captain in the Israeli army, he had planned to graduate, work as a manager in a hi-tech company, and raise a family. Those plans changed drastically when he was told he would have 2-5 years to live, and that the medical establishment could do nothing for him. Kremer’s business perspective sparked his interest in the economics of ALS therapies, and inspired him to use his Harvard training to work for a cure.

Little is known about what causes ALS and only a few companies develop ALS drugs, so Kremer and two of his Harvard colleagues queried scientists and industry executives about the gaps that have prevented researchers from finding a cure. Companies said that they needed some basic research tools to reduce the cost of the development, like a biomarker – a better way to track disease progression. So Kremer and his classmates began Prize4Life, Inc., a non-profit organization employing business theories to stimulate research, which announced in 2006 that they would give $1 million to anyone who could come up with such a biomarker. The ALS Biomarker Prize program recently awarded $100,000 in progress prizes, and the organization’s second prize, the Avi Kremer ALS Treatment Prize, hits its one-year anniversary in October 2009.

While prizes are the visible core of our results-oriented model, we are also conscious of the need to create a vibrant and supportive arena in which our participating teams can effectively compete. Prize4Life has thus created a series of innovative projects and partnerships, piggybacking on its groundbreaking prize model, to ensure that all competing teams equal opportunity to be successful.

As one example of such partnership: in June 2009, Prize4Life and the Alzheimer Research Forum announced the launch of a new ALS-focused internet portal known as the ALS Forum (http://www.researchALS.org). Initial reaction to the new web portal has been swift and positive. The site offers ALS researchers around the world a one-stop access point for cutting edge research news and unique web-based resources. We also have designed and developed a manual to help researchers design their animal trials, and are currently designing and developing a database of genes associated with ALS that we intend to make available to researchers.

About Prize4Life
Prize4Life was founded by a group of Harvard Business School students when one of them, Avi Kremer, was diagnosed with ALS at the age of 29. Prize4Life works to accelerate the discovery of a treatment and a cure for ALS by using powerful incentives to attract new people and ideas, and to leverage existing efforts and expertise in the ALS field. Among other program initiatives, the organization currently administers the ALS Biomarker Prize Challenge, the Avi Kremer ALS Treatment Prize, and the ALS Forum.

THE NEXT ALS BREAKTHROUGH COULD BE YOURS

Meghan also shared with me an example of a successful outreach effort using the competition model. “We actually awarded $50,000 to a dermatologist who had never studied ALS before, and who was intrigued by the prize model, and who submitted a winning entry, which is a testament to the potential of the prize model itself.” For the complete press release with much additional information, see the press release, “Prize4Life Awards Prizes for ALS Biomarker Challenge to InnoCentive Solvers: Extends $1Million Challenge Seeking ALS Biomarker” (PDF).

Further examples of great collaboration can be seen in their press release, “Prize4Life and The Jackson Laboratory partner in fight against ALS
Non-profits join forces to provide researchers with new preclinical resources
” (PDF). This describes a partnership with The Jackson Laboratory (JAX®), the world’s leading provider of mouse models, to provide preclinical resources for ALS research. Together, Prize4Life and JAX® have prepared a comprehensive training manual to enable researchers to more effectively use the SOD1 mouse model in the fight against ALS.

Their website is http://www.prize4life.org.

Want to Help?
If you would like to help, Meghan told me that there are many opportunities. “We always need donations and fundraisers (this is the link), but we also have folks who host events for us, who blog on our behalf (on their blogs or on ours), who reach out to scientists who may want to compete for our prizes, to follow us on Facebook and Twitter, to link to us on their sites, the list goes on! We have an exciting event coming up here in Boston, for those who are local–Boston’s pro lacrosse team will be featuring us at ‘Heroes Awareness Night’ at the Boston TD Garden on February 6, and donating a percentage of the proceeds to our efforts. If anyone is on the east coast and wants to attend, they should click here:http://bit.ly/512shV. Anyone interested can contact me directly, mkallman at prize4life dot org.

A great example of collaborative innovation in action, with bonus points for using innovation competitions and having altruistic goals. ALS is a terrible disease and needs more attention in the quest for cure.

Swine flu spawns innovative video game

iStock_000004797384SmallAs I was catching up on news and world events this morning one story caught my eye about a company that has come up with an innovative way to raise awareness about swine flu: a video game!

Dutch researchers say their game challenges players to control the flu.

Here is a snippet from the Associated Press article:

“It is actually what is happening now, what is happening in the real world,” said Albert Osterhaus, head of virology at the Erasmus Medical Center, who designed “The Great Flu” game with colleagues.

The game can only be played online at http://www.thegreatflu.com and it is free. A World Health Organization spokesman said Monday the agency was not familiar with the game and had not had time to play it.

The game begins with images of bedridden patients and graveyards from the 1918 Spanish flu. As the head of the fictitious “World Pandemic Control,” players pick a flu strain, and then monitor that strain’s spread around the world.

To fight the emerging outbreak, players use measures including setting up surveillance systems, stockpiling antivirals and vaccines, and closing schools and airports. Players also have a limited budget and are warned that “your actions to control the virus cost money, so keep an eye on it.”

A running tally of the numbers of people infected and those who have died sit above the budget. Newspaper stories about the deadly virus and the global response to it — like riots breaking out worldwide — pop up to help players monitor the outbreak.

Messages from governments mirror the difficulties faced by international agencies like WHO. For instance, when players set up costly surveillance systems, the game often relays a message from governments that “we will comply with your directions…but we must inform you that the political support for this action is low in this region. Therefore, the effectiveness of the system may differ from your expectations.”

Osterhaus said the video game’s approximation of combating a pandemic, choosing between various interventions yet still watching the outbreak spread, gives people a sense of how difficult it is to make decisions in the public health world.

No doubt a number of trends and inventions will result from the H1N1 pandemic. The World Health Organization (WHO) says there are some 178,000 cases of swine flu. That includes nearly 15-hundred deaths worldwide. Medical experts from all countries have tried different methods to slow it down as pharmaceutical companies work to produce an effective vaccine.

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Food Trends: Processors Feel the Bite of the Economy

I’ve been looking at trends in the food manufacturing realm lately, and while the processors are feeling the crunch of our economic climate as are most businesses, some analysts are predicting big problems in store for the entire industry.

In fact author Hank Cardello, a food industry expert and author of Stuffed: An Insider’s Look at Who’s REALLY Making America Fat, says that food processors need to pay much closer attention to emerging health trends and not just the economy. He predicts that if manufacturers don’t stop producing overweight foods, they could face a fate similar to auto manufacturers who continued to produce overweight cars with a focus on short-term profits and a lack of innovation.

This former executive at Coca-Cola  even compares gas guzzlers in the auto industry to “weapons of mass consumption,” and talks about how products like the 14-hundred calorie Hardees Thickburger is equally to blame.  I can’t say as I disagree with him. Remember how the auto manufacturers missed the market signal that “smaller is better?” Remember when gas prices rose to $4 per gallon how consumers quickly began to look for more efficient cars?

With the food industry giving us more than 30 percent more calories than in the 1950s, perhaps it’s time for these processors to look at trends more seriously and re-invent their offerings.

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